FOMO26

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Welcome to FOMO26

The Foundation Model Challenge for Brain MRI at MICCAI 2026

Same core philosophy as FOMO25, now expanded with 306,303 brain MRI scans for pretraining and seven downstream tasks evaluating generalization in realistic clinical settings.

University of Copenhagen Harvard Medical School Pioneer Centre for AI A. A. Martinos Center Mass General Hospital Johns Hopkins University Radiological AI Testcenter Bispebjerg Hospital Gentofte Hospital Copenhagen Research Centre for Biological and Precision Psychiatry Cerebriu Neurobiology Research Unit Rigshospitalet
FOMO26 registration and full documentation will open soon.

Towards Clinical-Grade Foundation Models:

The FOMO26 Challenge Setup

Track 1: Methods

Pretrain on FOMO300K.

Participants pretrain using the official FOMO26 large-scale dataset to compare methods under a shared data regime.

Comprehensive code-release.

Track 2: Open

Pretrain on Any Data.

Participants may use additional public/private data and custom pipelines to maximize generalization.

Open-data and proprietary pipelines allowed.

Evaluation

Few-shot and out-of-domain clinical benchmarks.

As in FOMO25, all methods are evaluated on clinically relevant downstream tasks; FOMO26 expands the suite with additional tasks and broader scanner/domain coverage.

No restrictions on fine-tuning strategy unless explicitly stated in task rules.

FOMO300K is available on Hugging Face.

Timeline

April 2026

Challenge registration opens. Access to pretraining dataset and finetuning data. Public GitHub repo with example pretraining and finetuning code (MAE + U-Net) released.

15 May 2026

Sanity-check pipeline on Synapse opens — technical validation to confirm containers are correctly configured.

15 June 2026

Validation leaderboard opens. Final submission pipeline opens.

21 August 2026

Challenge submission deadline.

MICCAI 2026 — 4 or 8 October

Results announced. Top teams present their methods.

Tasks

Seven downstream tasks spanning classification, segmentation, regression, and representation quality. Tasks 1–3 continue from FOMO25; Tasks 4–7 are new.

Task 1

Infarct Classification

Few-shot binary classification of acute ischemic infarcts from clinical MRI acquired in Denmark and India.

Type: Classification (few-shot)
Modality: Clinical MRI (multi-sequence)
Metric: AUROC
Task 2

Meningioma Segmentation

Few-shot segmentation of meningioma tumors from clinical brain MRI.

Type: Segmentation (few-shot)
Modality: Clinical MRI
Metric: DSC + NSD
Task 3

Brain Age Estimation

Regression of chronological brain age from T1w and T2w MRI scans across a broad age range.

Type: Regression
Modality: T1w + T2w MRI
Metric: MAE + Correlation coefficient
Task 4 — New

Trigeminal Neuralgia Segmentation

Multiclass segmentation of the trigeminal nerve and surrounding vessels, relevant to surgical planning.

Type: Segmentation (multiclass)
Modality: T1w MRI
Metric: DSC + NSD
Task 5 — New

Polymicrogyria Classification

Few-shot binary classification of polymicrogyria, a rare cortical malformation, from T1w MRI.

Type: Classification (few-shot)
Modality: T1w MRI
Metric: AUROC
Task 6 — New

Linear Probing

Embedding quality assessment via linear separability — no fine-tuning allowed. Measures what the model learned during pretraining.

Type: Representation quality
Constraint: No fine-tuning
Metric: OvR AUROC + F1
Task 7 — New

Bias and Fairness

Group fairness evaluation using the same linear probing setup as Task 6. Assesses whether embeddings encode or suppress demographic and acquisition biases.

Type: Fairness evaluation
Constraint: No fine-tuning (same setup as Task 6)
Metric: OvR AUROC + F1 across demographic groups

Team

Organizing Committee

Stefano Cerri Lead Organizer
University of Copenhagen & Pioneer Centre For AI
Asbjørn Munk Lead Organizer
University of Copenhagen & Pioneer Centre For AI
Jakob Ambsdorf
University of Copenhagen & Pioneer Centre For AI
Sebastian Nørgaard Llambias
University of Copenhagen & Pioneer Centre For AI
Julia Machnio
University of Copenhagen & Pioneer Centre For AI
Pablo Rocamora García
University of Copenhagen & Pioneer Centre For AI
Zahra Sobhaninia
University of Copenhagen & Pioneer Centre For AI
Mostafa Mehdipour Ghazi
University of Copenhagen & Pioneer Centre For AI
Alice Schiavone
University of Copenhagen
Leila Khaertdinova
University of Copenhagen
Simon Winther Albertsen
University of Copenhagen
Said Djafar Said
University of Copenhagen
Bulat Ibragimov
University of Copenhagen
Melanie Benjamin Ganz
University of Copenhagen & Copenhagen University Hospital, Rigshospitalet
Llucia Coll
Copenhagen University Hospital, Rigshospitalet
Christian Hedeager Krag
Radiological AI Testcenter, Denmark
Mikael Ploug Boesen
Radiological AI Testcenter & Copenhagen University Hospital
Espen Jimenez Solem
Copenhagen University Hospital
Vardan Nersesjan
Copenhagen University Hospital, Rigshospitalet
Michael Eriksen Benros
Mental Health Centre Copenhagen & University of Copenhagen
Juan Eugenio Iglesias
MGH / Harvard Medical School & MIT
Peirong Liu
Johns Hopkins University
Risheng Xu
Johns Hopkins University
Mads Nielsen
University of Copenhagen & Pioneer Centre For AI

News

Announcing FOMO26

April 3, 2026

We are excited to announce FOMO26, the Foundation Model Challenge for Brain MRI at MICCAI 2026. Full documentation and registration details will be published soon.

Join the Challenge

Interested in participating, sponsoring, or collaborating? Reach out and we will notify you when full registration opens.

Contact information will be published when registration opens.